Event Details - Center of Integrated Biomedical and Bioengineering Research

Kevin W. Plaxco, Professor and Vice Chair; Director of the Center for Bioengineering, Department of Chemistry & Biochemistry, Biomolecular Science and Engineering, University of California, Santa Barbara.

"Counting molecules, dodging blood cells: continuous, real-time molecular measurements directly in the living body" 

 The availability of technologies capable of tracking the levels of drugs, metabolites, and biomarkers in real time in the living body would revolutionize our understanding of health and our ability to detect and treat disease. Imagine, for example, a dosing regime that, rather than relying on your watch (“take two pills twice a day”), is instead guided by second-to-second measurements of plasma drug levels wirelessly communicated to your smartphone. Such a technology would likewise provide researchers and clinicians an unprecedented window into neurology and physiology, and could even support ultra-high-precision personalized medicine in which drug dosing is optimized minute-byminute using closed-loop feedback control. Towards this goal, we have developed a biomimetic, electrochemical sensing platform that supports the high frequency, real-time measurement of specific molecules